Micro-rna-based compositions and methods for the diagnosis,...

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A61K 31/7105 (2006.01) A61K 31/7088 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) C12N 15/113 (2010.01)

Patent

CA 2734179

Methods for assessing a pathological condition in a subject includes measuring an expression profile of one or more markers where a difference is indicative of multiple myeloma (MM) or a predisposition to MM. The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of MM. The invention also provides methods of identifying anti-MM cancer agents.

La présente invention concerne des procédés dévaluation dune condition pathologique chez un sujet qui comprend la mesure dun profil dexpression dun ou de plusieurs marqueurs, une différence indiquant un myélome multiple (MM) ou une prédisposition au MM. La présente invention concerne de nouveaux procédés et de nouvelles compositions pour le diagnostic, le pronostic et le traitement du MM. Linvention concerne également des procédés didentification dagents anticancéreux contre le MM.

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