Immunogenic peptides derived from mage and the use thereof

Details Immunogenic peptides derived from mage and the use thereof Immunogenic peptides derived from mage and the use thereof

C - Chemistry, Metallurgy

12

N

C12N 5/08 (2006.01) A61K 35/12 (2006.01) A61K 39/385 (2006.01) C07K 14/47 (2006.01) C07K 16/28 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2374354

Peptides derived from proteins of the MAGE family and the use thereof as immunogenic agents in the treatment of tumors, the compositions containing them, a method for inducing a cytotoxic response against tumor cells, a melanoma cell line not expressing histocompatibility antigens and the applications thereof.

L'invention concerne des peptides dérivés de protéines de la famille MAGE, ainsi que l'utilisation de ceux-ci en tant qu'agents immunogènes dans le traitement de tumeurs. Elle concerne également des compositions contenant ces peptides, un procédé d'induction d'une réponse cytotoxique contre des cellules tumorales, une lignée cellulaire de mélanome exprimant des antigènes d'histocompatibilité, ainsi que des applications de ceux-ci.

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