Transdermal absorption preparation

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/34 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 9/12 (2006.01) A61K 9/70 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2489188

A transdermal absorption promotion composition comprising the following components (a), (b), and (c) and a transdermal absorption preparation comprising the following components (a), (b), (c), and (d) are disclosed. (a) propylene glycol (b) a polyol fatty acid ester (c) lauromacrogol (d) a drug component The transdermal absorption promotion composition and transdermal absorption preparation not only exhibit an excellent transdermal absorption promotion effect, but also exhibit superior skin-permeability, even if a drug having a relatively high lipophilic property and poor transdermal absorbability is used, exhibit a favorable feeling of use, and are safe and stable.

L'invention porte: sur une composition favorisant l'absorption transdermique contenant les éléments (a), (b), et (c) suivants, et sur une préparation à absorption transdermique contenant les éléments (a), (b), (c) et (d) suivants qui sont: (a) du propylèneglycol, (b) un polyol ester d'acide gras, (c) du lauromacrogol et (d) un médicament. On obtient ainsi: une composition favorisant l'absorption transdermique, sûre et stable, qui non seulement favorise l'absorption transdermique, mais rend des médicaments assez fortement lipophiles et à faible absorption transdermique capables de traverser la peau tout en présentant une texture en favorisant l'utilisation; et sur une préparation à absorption transdermique contenant de plus un médicament.

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