2-phenyl-2h-pyraz0le derivatives as p2x7 receptor...

Details 2-phenyl-2h-pyraz0le derivatives as p2x7 receptor... 2-phenyl-2h-pyraz0le derivatives as p2x7 receptor...

C - Chemistry, Metallurgy

07

D

C07D 231/38 (2006.01) A61K 31/415 (2006.01) A61K 31/416 (2006.01) A61K 31/4162 (2006.01) A61K 31/4439 (2006.01) A61P 29/00 (2006.01) C07D 231/54 (2006.01) C07D 401/12 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2628260

A compound having formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the description., is disclosed as an P2X7 antagonist. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.

L'invention concerne un composé représenté par la formule (I), dans laquelle R1, R2, R3, R4, R5 et R6 sont tels que définis dans la description, qui est un antagoniste des P2X7. L'invention concerne également des méthodes et des compositions pour le traitement d'une maladie ou d'un état modulés par les P2X7.

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