Methods for manipulating moieties in microfluidic systems

G - Physics – 01 – N

Patent

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Details

G01N 1/00 (2006.01) C12N 13/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2417341

This invention relates generally to the field of moiety or molecule manipulation in a chip format. In particular, the invention provides a method for manipulating a moiety in a microfluidic application, which method comprises: a) coupling a moiety to be manipulated onto surface of a binding partner of said moiety to form a moiety-binding partner complex; and b) manipulating said moiety-binding partner complex with a physical force in a chip format, wherein said manipulation is effected through a combination of a structure that is external to said chip and a structure that is built-in in said chip, thereby said moiety is manipulated.

Cette invention, qui a trait à la manipulation de fragments ou de molécules dans un dispositif au format de microplaquette, concerne, notamment, une technique de manipulation d'un fragment dans un système microfluidique. Cette technique consiste, (a), à installer un fragment à manipuler à la surface d'un partenaire de liaison afin de former un complexe partenaire de liaison fragment et, (b), à manipuler ce complexe en utilisant une force physique dans un dispositif au format de microplaquette, cette manipulation s'effectuant au moyen de la combinaison d'une structure extérieure à la microplaquette et d'une structure constituée dans la microplaquette.

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