Retinoic acid x-receptor ligands

Details Retinoic acid x-receptor ligands Retinoic acid x-receptor ligands

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

C

IPC codes

C07C 57/50 (2006.01) A61K 31/19 (2006.01) C07C 45/29 (2006.01) C07C 45/63 (2006.01) C07C 47/24 (2006.01) C07C 47/277 (2006.01) C07C 57/62 (2006.01) C07D 333/24 (2006.01) C07F 9/40 (2006.01)

Type

Patent

Patent number

CA 2196197

Description

Compounds of formula (I) SEE FORMULA I wherein R1-R7, R10, X and the dotted bond have the meaning given in the specification, bind selectively to retinoid RXR receptors and are useful as antiproliferative agents for dermatological and oncological indications.

Des composés de la formule (I), dans laquelle R<1>-R<7>, R<10>, X et la liaison en pointillé ont la notation donnée dans la description, se fixent sélectivement aux récepteurs RXR rétinoïdes et sont utiles comme agents antiprolifératifs pour des indications dermatologiques et oncologiques.

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