Compounds and their preparation for the treatment of...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 9/00 (2006.01) A61K 31/575 (2006.01) A61K 31/58 (2006.01) C07J 17/00 (2006.01)

Patent

CA 2573699

The present invention provides novel ginsenoside compounds, compositions (e.g. pharmaceutical compositions) comprising the ginsenoside compounds, and methods for the synthesis of these ginsenoside compounds. Additionally, the present invention provides methods for inhibiting beta-amyloid peptide production and methods for treating or preventing a pathological condition, particularly, neurodegeneration diseases (e.g. Alzheimer's disease), using these ginsenoside compounds.

La présente invention concerne de nouveaux composés de ginsenoside, des compositions (par ex., des compositions pharmaceutiques) renfermant ces composés de ginsenoside ainsi que des procédés de synthèse de ces composés de ginsenoside. En outre, la présente invention concerne des méthodes destinées à inhiber la production de peptides bêta-amyloïdes et des méthodes destinées à traiter ou prévenir un état pathologique, et notamment les maladies neurodégénératives (par ex., la maladie d'Alzheimer), au moyen de ces composés de ginsenoside.

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