C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 9/00 (2006.01) C07D 239/00 (2006.01) C07D 333/00 (2006.01)
Patent
CA 2387520
The invention relates to the amine derivatives of the formula (I), and to their physiologically acceptable salts and solvates, wherein R1, R2, R8, R9, R10, R11, Q, X, Y, Z, r, ring A and ring C have the meaning indicated in claim 1. The inventive derivatives are characterized by a phosphodiesterase-V inhibiting effect and are used for treating diseases of the cardiovascular system and for the treatment and/or the therapy of potency disorders.
La présente invention concerne des dérivés d'amine de formule (I), ainsi que leur sels et solvates physiologiquement acceptables. Dans la formule (I): R?1¿, R?2¿, R?8¿, R?9¿, R?10¿, R?11¿, Q, X, Y, Z, r, les composés cycliques A et C ont les significations indiquées dans la revendication (1). Ces composés permettent l'inhibition de la phosphodiestérase V et peuvent être utilisés pour le traitement de troubles du système cardio-vasculaire et pour le traitement et/ou la thérapie de troubles de puissance.
Eiermann Volker
Jonas Rochus
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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