C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 65/05 (2006.01) A61P 5/48 (2006.01) C07D 213/79 (2006.01) C07D 277/56 (2006.01) C07D 307/68 (2006.01) C07D 333/40 (2006.01) C07D 405/06 (2006.01)
Patent
CA 2529875
The present invention relates to compounds of formula (1) wherein R1, R2 , R3 , R4 , m, n, p and s are as defined in the description and claims, and pharmaceutically acceptable salts thereof and to pharmaceutical compositions thereof. The compounds are useful for the treatment and/or prophylaxis of diseases that are associated with the activation of the glycogen synthase enzyme, such as diabetes.
L'invention porte sur des composés de formule (I) dans laquelle: R?1¿, R?2¿, R?3¿, R?4¿, m, n, p et s sont définis dans la description et les revendications, et sur leurs sels pharmacocompatibles. Lesdits composés s'avèrent utiles pour le traitement et la prophylaxie de maladies, telles que le diabète, associées à l'enzyme glycogène synthase.
Chu Chang An
Gillespie Paul
Tilley Jefferson Wright
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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