Pretreatment with growth factors to protect against cns damage

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/18 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2266659

Methods for protecting neural tissue from the effects of aging, trauma, toxic insult, neurological diseases or disorders comprise administering growth factors to the neural tissue of a mammal at a time prior to the onset of trauma or the manifestations of neurological disease or aging. The growth factors induce multipotent neural stem cells and neural stem cell progeny to proliferate and generate new neural cells which provide supportive and protective roles against the effects of aging, trauma, toxic insult, neurological diseases or disorders.

L'invention concerne des procédés de protection des tissus neuraux contre les effets du vieillissement, contre des lésions, des agressions toxiques, des troubles ou maladies neurologiques, ces procédés consistant à administrer des facteurs de croissance aux tissus neuraux d'un mammifère, préalablement à l'apparition d'une lésion ou avant toute manifestation de maladie neurologique ou du vieillissement. Les facteurs de croissances induisent la prolifération de cellules souches neurales pluripotentes et de la descendance de cellules souches neurales ainsi que la production de nouvelles cellules neurales jouant un rôle de support et de protection contre les effets du vieillissement, contre des lésions, des agressions toxiques, des troubles ou maladies neurologiques.

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