Method and composition for treatment of osteoporosis

Details Method and composition for treatment of osteoporosis Method and composition for treatment of osteoporosis

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 31/57 (2006.01) A61K 33/00 (2006.01)

Patent

CA 2159354

The combination of the following active ingredients for treating osteoporosis: (a) a pharmaceutically-acceptable alkalinizing potassium salt which produces hydroxyl ions and is thereby capable of reducing the acidity of tissue fluids or urine and which is selected from the group consisting of potassium bicarbonate and potassium salts of carboxylic acids which are transformed to bicarbonate and thus alkalinize in vivo; and (b) an estrogen which is effective in the treatment of osteoporosis, in an amount of as little as 1/10 its normal recommended dose; the alkalinizing potassium salt being present in an amount such that the combination is substantially more effectie in treating osteoporosis than the same amount of the estrogen when independently administered.

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