Novel pharmaceutical

Details Novel pharmaceutical Novel pharmaceutical

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/427 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2370270

5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, hydrochloride monohydrate characterised in that it: (i) provides an infra red spectrum containing peaks at 3358, 2764, 1245, 833 and 760 cm-1; and/or (ii) provides an X-ray powder diffraction (XRPD) pattern containing peaks at 15.0, 17.7, 23.0, 30.0 and 31.4 ~2.theta.; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound in medicine.

La présente invention concerne un monohydrate d'hydrochlorure 5-[4-[2-(N-méthyl-N-(2-pyridyl)amino)éthoxy]benzyl]thiazolidine-2,4-dione qui se caractérise en ce qu'il: (i) produit un spectre infrarouge contenant des pics à 3358, 2764, 1245, 833 et 760 cm?-1¿; et/ou (ii) produit un diagramme de diffraction de la poudre aux rayons X qui comporte des pics à 15,0; 17,7; 23,0; 30,0 et 31,4 ·2.theta.. On décrit également un procédé de préparation de ce composé, une composition pharmaceutique contenant ce même composé et l'utilisation de ce dernier en médecine.

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