G-protein coupled receptor related polypeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2401549

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecificlly-bind o the polypeptide, as well as derivatives, variants, mutants, or fragments or the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention se rapporte à des séquences d'acides nucléiques qui codent pour des polypeptides associés à des récepteurs-protéines couplés à une protéine G. L'invention se rapporte à des polypeptides codés par ces séquences d'acides nucléiques, et à des anticorps qui se lient de manière immuno-spécifique audit polypeptide, ainsi qu'à des dérivés, variants, mutants ou fragments du polypeptide, polynucléotide ou anticorps ci-dessus mentionné. L'invention se rapporte en outre à des méthodes thérapeutiques, diagnostiques et de recherche permettant le traitement, le diagnostic et la prévention de troubles impliquant n'importe lequel de ces nouveaux acides nucléiques ou n'importe laquelle de ces nouvelles protéines d'origine humaine.

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