Indole compounds having c4-acidic substituents and use...

Details Indole compounds having c4-acidic substituents and use... Indole compounds having c4-acidic substituents and use...

C - Chemistry, Metallurgy

07

D

C07D 209/32 (2006.01) A61K 31/405 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2627353

Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.

L'invention concerne de l'indole et des composés apparentés à l'indole, des compositions et des méthodes. Les composés de l'invention sont utiles en tant qu'inhibiteurs de phospholipases. Les composés et compositions de l'invention sont utiles pour le traitement d'états liés aux phospholipases, tels que les états liés à l'insuline, liés au poids et/ou au cholestérol chez un sujet animal.

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