Oxamide derivatives useful as raf-kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 213/68 (2006.01) A61K 31/4427 (2006.01) A61P 17/06 (2006.01) A61P 31/00 (2006.01) C07D 213/81 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2520009

The present invention relates to oxamide derivatives of Formula (I), the use of the compounds of Formula (I) as inhibitors of raf-kinase, the use of the compounds of Formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.

La présente invention concerne des dérivés oxamidiques représentés par la formule (I). L'invention concerne également l'utilisation des tels composés représentés par la formule (I) comme inhibiteurs de la raf-kinase, et leur utilisation pour la fabrication d'une composition pharmaceutique. L'invention concerne enfin des procédés thérapeutiques comprenant l'administration de cette composition pharmaceutique à un patient.

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