Use of methylnaltrexone in treating gastrointestinal...

A - Human Necessities – 61 – K

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A61K 31/64 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2475305

Systems and methods are described for using methylnaltrexone in treating inhibition of gastrointestinal motility in equines. A method for preventing and treating opioid-induced and non-opioid-induced gastrointestinal dysfunction includes administering a quaternary derivative of noroxymorphone to an equine before or after the onset of the gastrointestinal dysfunction.

L'invention concerne des systèmes et des méthodes d'utilisation de la méthylnaltrexone dans le traitement de l'inhibition de la motilité gastro-intestinale chez les équidés. L'invention concerne une méthode de prévention et de traitement de la dysfonction gastro-intestinale induite par opioïdes et non induite par opioïdes qui consiste à administrer un dérivé quaternaire de la noroxymorphone à un équidé avant ou après le début de la dysfonction gastro-intestinale.

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