P38 map kinase inhibitors and methods for using the same

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/4162 (2006.01) C07D 231/56 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2620254

Compounds of formula Ia or Ib; wherein A, W, X, Y, R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.

L'invention concerne des composés de formule Ia ou Ib. Dans cette formule, A, W, X, Y, R1, R2, R3 et R4 sont définis dans la description. L'invention concerne également des méthodes de fabrication des composés susmentionnés et des méthodes d'utilisation de ces composés pour le traitement de maladies médiées par la MAP-kinase p38.

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