Medical implants with a combination of compounds

Details Medical implants with a combination of compounds Medical implants with a combination of compounds

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61F 2/01 (2006.01) A61F 2/06 (2006.01) A61F 2/14 (2006.01) A61F 2/82 (2006.01) A61K 9/00 (2006.01) A61K 31/337 (2006.01) A61K 47/30 (2006.01) A61L 27/14 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) A61L 29/14 (2006.01) A61L 29/16 (2006.01) A61L 31/04 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01) A61M 25/10 (2006.01)

Patent

CA 2672496

Implants are associated with a combination of paclitaxel or derivatives and dipyridamole or derivatives in order to inhibit fibrosis that may otherwise occur when the implant is placed within an animal. Exemplary implants include intravascular implants (e.g., coronary and peripheral vascular stents, catheters, balloons), non-vascular stents, pumps and sensors, vascular grafts, perivascular devices, implants for hemodialysis access, vena cava filters, implants for providing an anastomotic connection, electrical devices, intraocular implants, and soft tissue implants and fillers.

L'invention concerne des implants qui sont associés à une combinaison de paclitaxel ou de dérivés de celui-ci et de dipyridamole ou de dérivés de celui-ci afin d'inhiber la fibrose qui peut sinon se produire lorsque l'implant est placé à l'intérieur d'un animal. Des implants à titre d'exemples comprennent des implants intravasculaires (par exemple, des stents vasculaires coronaires et périphériques, des cathéters, des ballonnets), des stents non vasculaires, des pompes et des détecteurs, des greffes vasculaires, des dispositifs périvasculaires, des implants pour un accès par hémodialyse, des filtres de veine cave, des implants pour fournir une connexion anastomotique, des dispositifs électriques, des implants intra-oculaires et des implants et charges de tissu mou.

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