Novel collagen formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/42 (2006.01) A61K 9/00 (2006.01) A61K 31/135 (2006.01) A61K 31/215 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2218037

Disclosed are proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition temperature of less than about 45 ~C. Such compositions possess enhanced retention of the cytotoxic drug at the site of injection and are optically translucent.

La présente invention concerne des compositions protéiniques comprenant du collagène et une quantité efficace d'un médicament cytotoxique compatible, ces compositions étant caractérisées par une température unique de transition du collagène inférieure à 45 ·C environ. De telles compositions, qui présentent une aptitude accrue à la rétention du médicament cytotoxique au niveau du site d'injection, sont optiquement translucides.

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