Solid forms comprising...

A - Human Necessities – 61 – K

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A61K 31/4035 (2006.01)

Patent

CA 2718601

Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2- methylsulfonylethyl]-4-acetylaminoisoindoline--1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-.alpha. or the inhi-bition of PDE4.

La présente invention concerne des formes solides comprenant de la (+)-2-[l-(3-éthoxy-4-méthoxyphényl)-2- méthylsulfonyléthyl]-4-acétylaminoisoindoline-l,3-dione, des compositions comprenant les formes solides, des procédés permettant de fabriquer les formes solides et des procédés permettant leur utilisation. Les procédés comprennent des procédés permettant de traiter et/ou prévenir des troubles améliorés par la réduction des taux de TNF-a ou linhibition de PDE4.

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