A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4035 (2006.01)
Patent
CA 2718601
Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2- methylsulfonylethyl]-4-acetylaminoisoindoline--1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-.alpha. or the inhi-bition of PDE4.
La présente invention concerne des formes solides comprenant de la (+)-2-[l-(3-éthoxy-4-méthoxyphényl)-2- méthylsulfonyléthyl]-4-acétylaminoisoindoline-l,3-dione, des compositions comprenant les formes solides, des procédés permettant de fabriquer les formes solides et des procédés permettant leur utilisation. Les procédés comprennent des procédés permettant de traiter et/ou prévenir des troubles améliorés par la réduction des taux de TNF-a ou linhibition de PDE4.
Ge Chuansheng
Man Hon-Wah
Muller George W.
Schafer Peter H.
Xu Jean
Celgene Corporation
Smart & Biggar
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