Tadg-15: an extracellular serine protease overexpressed in...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2324993

The present invention provides a DNA encoding a TADG-15 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-15 protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes a TADG-15 protein; and (c) isolated DNA differing from the isolated DNAs of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression in a recombinant cell and regulatory elements necessary for expression of the DNA in the cell.

La présente invention concerne un ADN codant une protéine TADG-15 sélectionné dans le groupe constitué par: a) un ADN isolé codant une protéine TADG-15; b) un ADN isolé s'hybridant avec l'ADN isolé décrit sous a) et codant une protéine TADG-15; et c) un ADN isolé différent des ADN isolés décrits sous a) et b) dans une séquence codon (différence est imputable à la dégénérescence du code génétique) et codant une protéine TADG-15. L'invention concerne également un vecteur pouvant exprimer l'ADN de l'invention et se prêtant à une expression dans une cellule recombinante. L'invention concerne enfin des éléments régulateurs nécessaires pour l'expression de l'ADN dans la cellule.

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