Benzothiozaline derivatives, process for their preparation...

Details Benzothiozaline derivatives, process for their preparation... Benzothiozaline derivatives, process for their preparation...

C - Chemistry, Metallurgy

07

D

167/211, 167/234

C07D 277/82 (2006.01) A61K 31/425 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2005591

Compounds with the formula: (see Fig. I) in which, - R1 represents a polyfluoroalkoxy radical and - R2 represents an alkyl, alkenyl (C3-6), cycloalkyl alkyl (C3-6), carbamoylalkyl, dialkylcarbamoylalkyl, - acylaminoalkyl, phenylthioalkyl, hydroalkyl; cyanoalkyl, sulfamoylethyl, N-alkylsulfamoylethyl, pyridylthioalkyl, pyridylalkylthioalkyl; pyridylsulfinylalkyl, alkynyl (C3-6), phenylsulfinylalkyl, halogenophenylthioalkyl, (trifluoro-2,2,2 ethyl) thioalkyl, dialkylamino-2 propyl, pyrimidinylsulfinalkyl, pyridylalkylsul- finylalkyl, halogenophenylsulfinylalkyl or (trifluoro-2,2,2 ethyl) sulfinylalkyl radical, their salts, their preparation processes and the medications containing them.

BREVET D'INVENTION DERIVES D'IMINO-2 POLYFLUOROALCOXY-6 BENZOTHIAZOLINE, LEURS PROCEDES DE PREPARATION ET LES MEDICAMENTS LES CONTENANT RHONE-POULENC SANTE ABREGE Composés de formule : (I) Image dans laquelle, - R1 représente un radical polyfluoroalcoxy et - R2 représente un radical alkyle, alcényle (3-6 C), cycloal- kyl(3-6 C) alkyle, carbamoylalkyle, dialkylcarbamoylalkyle, acylami- noalkyle, phénylthioalkyle, hydroxyalkyle, cyanoalkyle, sulfamoyl- éthyle, N-alkylsulfamoyléthyle, pyridylthioalkyle, pyridylalkylthio- alkyle, pyridylsulfinylalkyle, alcynyle (3-6 C), phénylsulfinylal- kyle, halogénophénylthioalkyle, (trifluoro-2,2,2 éthyl) thioalkyle, dialkylamino-2 propyle, pyrimidinylsulfinylalkyle, pyridylalkylsul- finylalkyle, halogénophénylsulfinylalkyle ou (trifluoro-2,2,2 éthyl) sulfinylalkyle leurs sels, leurs procédés de préparation et les médicaments les contenant.

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