Methods and computer software products for predicting...

G - Physics – 06 – F

Patent

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G06F 17/00 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2363518

Methods and computer software products are provided for predicting nucleic acid hybridization affinity. In one embodiment, hybridization intensity (I) is determined using the equation: (see formula I) where Pi is the value of the ith parameter and Si is a value derived from the sequence of the probe. The methods and software products of the invention may be used for enhancing mutation detection, probe selection and probe array manufacturing quality control.

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