C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A01K 67/00 (2006.01) A01K 67/027 (2006.01) A01N 43/04 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) C07K 14/47 (2006.01) C12N 5/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/66 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2377434
This invention relates to compositions and methods for selective expression of a heterologous nucleic acid sequence in a targeted tissue, and more particularly to the glucose regulated protein 78 (grp78) stress-responsive promoter and its use in gene therapy and the production of transgenic animals.
La présente invention concerne des compositions et des procédés destinés à l'expression sélective d'une séquence d'acide nucléique hétérologue dans un tissu cible, et concerne plus particulièrement le promoteur de réaction au stress de la grp 78 (glucose regulated protein), et son utilisation en thérapie génique et dans la production d'animaux transgéniques.
Smart & Biggar
University Of Southern California
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