A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/165 (2006.01)
Patent
CA 2588052
The present invention features pharmaceutical compositions that improve the bioavailability of hydrophobic pharmaceutical agents that induce apoptosis in mammalian cells. Also featured are injectable formulations for the parenteral delivery of such hydrophobic pharmaceutical agents into patients in need of such treatment, as well as methods of making and using both the compositions and formulations, including methods for the treatment of cell proliferation or hyperproliferative diseases and disorders.
La présente invention concerne des compositions pharmaceutiques augmentant la biodisponibilité d'agents pharmaceutiques hydrophobes induisant l'apoptose dans des cellules de mammifères. L'invention concerne également des préparations injectables pour l'administration parentérale de ces agents pharmaceutiques hydrophobes à des patients nécessitant un tel traitement, ainsi que des méthodes de fabrication et d'utilisation de ces compositions et de ces préparations, y compris des méthodes pour le traitement de la prolifération cellulaire ou de maladies et de troubles hyperprolifératifs.
Shih Chung
Zentner Gaylen M.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Myriad Genetics Inc.
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