Cathepsin cysteine protease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/04 (2006.01) A61K 31/275 (2006.01) C07C 255/19 (2006.01) C07C 255/25 (2006.01) C07C 255/46 (2006.01) C07C 311/37 (2006.01) C07C 317/32 (2006.01) C07C 317/44 (2006.01) C07D 209/08 (2006.01) C07D 213/24 (2006.01) C07D 213/38 (2006.01) C07D 213/57 (2006.01) C07D 213/64 (2006.01) C07D 213/70 (2006.01) C07D 213/89 (2006.01) C07D 215/12 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 239/26 (2006.01) C07D 241/12 (2006.01) C07D 261/08 (2006.01) C07D 263/32 (2006.01) C07D 271/06 (2006.01) C07D 2

Patent

CA 2477657

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

L'invention concerne une nouvelle classe de composés qui sont des inhibiteurs de cystéine protéase, notamment et de façon non exhaustive, des inhibiteurs de cathepsines K, L, S et B. Ces composés sont utiles pour traiter des maladies dans lesquelles une inhibition de la résorption osseuse est indiquée, telles que l'ostéoporose.

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