Use of tyrosine kinase inhibitors for promoting hair growth

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 8/49 (2006.01) A61K 31/015 (2006.01) A61K 31/095 (2006.01) A61K 31/40 (2006.01) A61K 31/403 (2006.01) A61K 31/404 (2006.01) A61K 31/415 (2006.01) A61K 31/4709 (2006.01) A61K 31/498 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/66 (2006.01) A61K 45/06 (2006.01) A61Q 7/00 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2461182

The present invention relates to a method for promoting hair growth, preventing or minimizing hair loss comprising administering a tyrosine kinase inhibitor to a human in a need of such treatment, more particularly a non- toxic, selective and potent c-kit inhibitor. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.

La présente invention concerne un procédé permettant de stimuler la pousse des cheveux ou bien d'empêcher ou de minimiser la perte des cheveux, ce procédé consistant à administrer un inhibiteur de tyrosine kinase à un homme nécessitant un tel traitement, plus particulièrement un inhibiteur de c-kit non toxique, sélectif et puissant. De préférence, ledit inhibiteur peut être utilisé pour stimuler la mort de cellules dépendantes de L'IL-3 mises en culture en présence de l'IL-3.

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