Method for using polynucleotides, oligonucleotides and...

Details Method for using polynucleotides, oligonucleotides and... Method for using polynucleotides, oligonucleotides and...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2153778

Oligodeoxyribonucleotides, polydeoxyribonucleotides and derivatives thereof, such as defibrotide, are agents of genetic modulation at the levels of transcription, translation, secondary messengers and cellular signal transduction systems. Various disease states can be treated by modifying the dose of such agents in response to observed fluctuations (e.g., increase, decrease, appearance, disappearance) in normal, disease and repair markers.

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