Means for regulating the expression of human isoforms of ant

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2513699

ARNi which can selectively inhibit expression of an isoform of ANT, characterized in that said ARNi are an ARN duplex, one of the strands being highly homologous to a fragment of ARNm coding for said isoform of ANT.

ARNi capables d'inhiber sélectivement l'expression d'une isoforme de l'ANT, caractérisés en ce qu'il s'agit d'un duplex d'ARN, l'un des brins étant hautement homologue d'un fragment de l'ARNm codant pour ladite isoforme de l'ANT.

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