Hiv immunogenic complexes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/18 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01) C07K 14/16 (2006.01) C07K 14/73 (2006.01) C07K 16/10 (2006.01) C07K 16/28 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2160922

A vaccine and a method of raising neutralizing antibodies against HIV infection. The vaccine comprises a complex of gp120 covalently bonded to CD4 or to succinyl concanavalin A. Also disclosed are immunological tests using the complex or antibody thereto for detection of HIV infection.

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