C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) C07H 21/00 (2006.01) C07K 14/245 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2402602
The present invention relates to products which are of nature B2+ A-, isolated from E. coli, and to their biological applications, in particular their medical (therapeutic, vaccine and diagnostic) and biotechnological applications. In the present application, the expression "of nature B2+ A-( is intended to mean presence at a frequency greater than 10 % among the E. coli strains of group B2 of the ECOR collection, and at a frequency of less than 10 % among the strains of group A of the same collection. A phylogenic determination method which makes it possible to rapidly and easily distinguish the groups A, B1, B2 and D of the E. coli species with more than 99 % precision is in particular described.
La présente invention concerne des produits de type B2+ A-, isolés d'E. coli, et leurs applications biologiques, notamment leurs applications médicales (thérapeutiques, vaccinales et diagnostiques) et biotechnologiques. Dans la présente invention l'expression <=de type B2+ A->= est utilisée pour signifier la présence à une fréquence supérieure à 10 % parmi les souches de E. coli de groupe B2 de la collection ECOR, et à une fréquence inférieure à 10 % parmi les souches de groupe A de la même collection. L'invention concerne également un procédé phylogénique permettant notamment de distinguer rapidement et aisément les groupes A, B1, B2 et D des espèces d'E. coli avec une précision supérieure à 99 %.
Bingen Edouard
Bonacorsi Stephane
Clermont Olivier
Nassif Xavier
Tinsley Colin
Assistance Publique-Hopitaux de Paris
Institut National de La Sante Et de La Recherche Medicale (i.n.s
Smart & Biggar
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