Construction of oncolytic adenovirus recombinant...

Details Construction of oncolytic adenovirus recombinant... Construction of oncolytic adenovirus recombinant...

C - Chemistry, Metallurgy

12

N

C12N 15/34 (2006.01) A61K 39/235 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2568995

The present invention relates to gene therapy for tumors, specifically, it relates to the construction of oncolytic adenovirus recombinant, which specifically expresses immune modulatory factor GM-CSF in tumor cells and uses thereof.

L'invention concerne la thérapie génique contre des tumeurs, notamment, la construction d'une recombinaison d'adénovirus oncolytique, qui exprime de façon spécifique un facteur immunomodulateur GM-CSF dans des cellules tumorales et utilisations correspondantes.

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