Thiourea derivatives and antimicrobial agent and antiulcer...

Details Thiourea derivatives and antimicrobial agent and antiulcer... Thiourea derivatives and antimicrobial agent and antiulcer...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/36 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 317/66 (2006.01) C07D 319/18 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2077122

Abstract of the Disclosure Thiourea derivatives represented by the formula (I) Image wherein R1 and R2 are the same or different and each represents a lower alkyl group, or R1 and R2 taken together represent a group having the formula -(CH2)x-CHR3-(CH2)y- in which R3 represents hydrogen or a lower alkyl group and x and y represent an integer of 0 to 2, respectively, A represents the formula -CH=CH- or -CH=N-, 1 is 1 or 2, m represents an integer of 0 to 2 and n represents an integer of 1 to 5. The thiourea derivatives possess an antiulcer activity and an antimicrobial activity against Helicobacter pyroli and are useful as an antiulcer agent and an antimicrobial agent against Helicobacter pyroli.

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