Analgesic methods using synthetic catalysts for the...

C - Chemistry – Metallurgy – 07 – F

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C07F 13/00 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2294155

Synthetic low molecular weight catalysts for the dismutation of superoxide are potent analgesics that are effective in elevating the pain threshold in hyperalgesic conditions such as arthritis, and also operate to prevent or reserve tolerance to opioid analgesics.

L'invention concerne des catalyseurs de synthèse à faible poids moléculaire utilisés pour la dismutation de superoxydes, qui constituent de puissants analgésiques permettant d'élever efficacement le seuil de sensibilité à la douleur dans des conditions d'hyperalgésie telles que par exemple l'arthrite, et qui permettent aussi d'éviter ou d'inverser la tolérance aux analgésiques opioïdes.

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