Biosynthetic gene ddl from streptococcus pneumoniae

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/52 (2006.01) C12N 9/00 (2006.01) C12Q 1/18 (2006.01) C12Q 1/25 (2006.01)

Patent

CA 2261155

The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene ddl of (Streptococcus pneumoniae). Also provided are vectors and transformed heterologous host cells for expressing the DDL enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.

Composés d'acide nucléique isolés codant le gène biosynthétique de pentapeptide dd1 de Streptococcus pneumoniae. Des vecteurs et des cellules hôtes hétérologues transformées exprimant le produit enzymatique DDL et un procédé d'identification de composés qui inhibent la biosynthèse des pentapeptides sont également décrits.

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