Reagents and methods for the detection and quantification of...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/44 (2006.01) C12N 5/20 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2216880

Immunoassay reagents, methods and test kits for the specific quantification of vancomycin in a test sample are disclosed. The reagent comprises antibodies prepared with immunogens of Figure 6 wherein P is an immunogenic carrier material and X is a linking moiety. Also described is the synthesis of labeled reagents of Figure 8 wherein Q is a detectable moiety, preferably fluorescein or a fluorescein derivative, and X is a linking moiety.

Réactifs de dosage immunologique, procédés et nécessaires d'essai pour la quantification spécifique de vancomycine dans un échantillon à analayser. Le réactif est constitué d'anticorps préparés à l'aide des immunogènes de la Figure 6, où P est un support immunogénique et X est une fraction de liaison. Est également décrite la synthèse de réactifs marqués de la figure 8, où Q est une fraction décelable, de préférence de la fluorescéine ou un dérivé de la fluorescéine, et X est une fraction de liaison.

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