Fluoroalkylamine derivatives as cathepsin inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 317/50 (2006.01) A61K 31/275 (2006.01)

Patent

CA 2610014

The present invention provides compounds of formula I which are inhibitors of cathepsin S and as such are useful in the prevention and treatment of cathepsin S dependent diseases and conditions including, but not limited to, chronic obstructive pulmonary disease (COPD) and pain.

L'invention concerne des composés de formule I qui sont des inhibiteurs de la cathepsine S et utiles dans la prévention et le traitement de maladies et d'états dépendants de la cathepsine S, notamment, mais sans caractère restrictif, la maladie pulmonaire obstructive chronique (MPOC) et des douleurs.

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