Improved host cells and culture methods

Details Improved host cells and culture methods Improved host cells and culture methods

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) C12N 9/24 (2006.01) C12N 15/52 (2006.01) C12N 15/67 (2006.01)

Patent

CA 2630782

lmproved host cells and culture methods involving over expression of MANlCl activity to improve protein production are provided.

La présente invention concerne des cellules hôtes améliorées et des procédés de culture comprenant la surexpression de l'activité de l'enzyme alpha 1,2-mannosidase I (MANICI) pour l'amélioration de la production de protéines.

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