Unsubstituted and substituted...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/84 (2006.01) A61K 31/4174 (2006.01) A61P 1/12 (2006.01) A61P 7/12 (2006.01) A61P 9/12 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2582071

Compounds of Formula 1 (I) where the variables have the meaning defined in the specification are used to activate alpha2 adrenergic receptors. The compounds of Formula 1 are incorporated in pharmaceutical compositions and are used as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2 adrenergic receptors.

L'invention concerne des composés représentés par la formule 1, dans laquelle les variables sont telles que définies dans les spécifications, et utilisés dans l'activation des récepteurs adrénergiques alpha2. Les composés représentés par la formule 1 sont incorporés dans des compositions pharmaceutiques et utilisés comme médicaments chez les mammifères, y compris les humains, pour le traitement de maladies et ou le soulagement d'états répondant au traitement utilisant des agonistes des récepteurs adrénergiques alpha2.

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