Peptide arginals and methods for treating disseminated...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/08 (2006.01) A61K 31/397 (2006.01) A61K 31/401 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61P 7/02 (2006.01) C07D 205/04 (2006.01) C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2457436

The invention relates to disseminated intravascular coagulation. More particularly, the invention relates to medical intervention for disseminated intravascular coagulation. The invention provides new peptides arginals, new and better compounds and methods for the treatment of DIC. The compounds and methods according to the invention have inhibitory action on clot-bound thrombin and factor Xa and are also inhibitory against plasmin and plasminogen activators.

L'invention se rapporte à la coagulation intravasculaire disséminée. Plus précisément, elle a trait à une intervention médicale pour traiter la coagulation intravasculaire disséminée. Cette invention porte sur de nouveaux peptides arginaux, sur de nouveaux et meilleurs composés, et sur des méthodes de traitement de la coagulation intravasculaire disséminée (CIVD). Ces composés et ces méthodes selon l'invention possèdent une action inhibitrice sur la thrombine liée au caillot et sur le facteur Xa ; ils présentent également une action inhibitrice contre la plasmine et les activateurs du plasminogène.

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