Cycloalkylsulfanyl substituted benzo[b]thiophenes as...

Details Cycloalkylsulfanyl substituted benzo[b]thiophenes as... Cycloalkylsulfanyl substituted benzo[b]thiophenes as...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/41 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2527341

The present invention provides benzo[b]thiophenes of Formula (I), wherein R1, R2, R3, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I).

La présente invention se rapporte à des benzo[b]thiophènes répondant à la formule (I), dans laquelle R?1¿, R?2¿, R?3¿ et L ont l'une quelconque des valeurs définies qui leur sont affectées dans la description, et leurs sels pharmaceutiquement acceptables, utilisables à titre d'agents dans le traitement de maladies et d'affections, notamment les maladies inflammatoires, les maladies cardio-vasculaires, et les cancers. L'invention se rapporte également à des compositions pharmaceutiques comportant un ou plusieurs composés répondant à la formule (I).

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