Methods and compositions for improved fertilization and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A01K 67/02 (2006.01) A61D 19/04 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01)

Patent

CA 2714824

Single nucleotide polymorphic sites at positions 19069 and 25402 of the bovine STAT3 gene are associated with improved fertilization rate and/or improved embryo survival rate. The interactions between these two polymorphisms, and between them and the bovine STAT1 gene and fertilization and early embryonic survival rates were also disclosed. The interactions between STAT3 SNPs, and between STAT1 and STAT3 SNP19069 were highly significant for embryonic survival rate. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods.

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