Methods of modeling migraine pain and identifying candidate...

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01) A61K 31/4045 (2006.01) A61K 31/417 (2006.01) A61K 31/5575 (2006.01) A61K 38/06 (2006.01) A61K 38/08 (2006.01) A61K 38/23 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2649454

The present invention features animal models of migraine pain that can be used in a variety of ways, e.g., to identify compounds that reduce migraine pain or other migraine symptoms, to investigate behavioral changes correlated with the development and maintenance of a migraine-like state, and to better understand the mechanisms that underlie migraine pain.

La présente invention concerne des modèles animaux de la douleur associée à la migraine pouvant être utilisés de différentes manières, par exemple pour identifier des composés réduisant la douleur de la migraine ou d'autres symptômes de la migraine, pour étudier les changements comportementaux mis en corrélation avec le développement et le maintien d'un état migraineux, et pour mieux comprendre les mécanismes liés à la douleur de la migraine.

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