Novel reporter gene construct for measuring g protein...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/65 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2224063

A reporter construct and recombinant cells transfected with this construct are provided which are useful for assaying compounds for the agonist or antagonist activity with respect to cell surface localized receptors. Assays methods using these recombinant cells are also provided.

Un construit rapporteur et des cellules recombinantes transfectées à l'aide de ce construit sont offerts; ces produits sont utiles pour vérifier l'activité agoniste ou antagoniste de composés à l'égard des récepteurs localisés sur la surface cellulaire. Des méthodes d'essai faisant intervenir ces cellules recombinantes sont également offertes.

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