Biomolecules comprising an elastomeric peptide

Details Biomolecules comprising an elastomeric peptide Biomolecules comprising an elastomeric peptide

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 14/00 (2006.01) C07K 14/31 (2006.01) C07K 14/47 (2006.01) C07K 14/78 (2006.01) C07K 16/10 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2301981

The present invention relates to biomolecules containing an inserted amino acid sequence comprising an elastomeric peptide which is inducibly contractible, which on contraction or extension alters the properties or characteristics of the molecule in which it is inserted, particularly biomolecules such as antibodies, nucleic acid molecules encoding such biomolecules and the use of such biomolecules.

La présente invention concerne des biomolécules contenant une séquence d'acides aminés qui y est introduite et comprenant un peptide élastomère pouvant se contracter de manière inductible et qui, lors d'une contraction ou d'une extension, modifie les propriétés ou les caractéristiques de la molécule dans laquelle il est introduit, notamment des biomolécules telles que des anticorps; l'invention concerne également des molécules d'acide nucléique codant ces biomolécules ainsi que l'utilisation de ces biomolécules.

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