A controlled slow release formulation of thiamine and use...

A - Human Necessities – 61 – K

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A61K 9/22 (2006.01) A61K 9/32 (2006.01) A61K 31/51 (2006.01)

Patent

CA 2580330

The present invention relates to thiamine controlled-release pharmaceutical compositions and their use in medicine for resolving absorption defects or deficiencies of thiamine itself from the organism. Said compositions have revealed to be useful in the treatment of cerebral pathologies connected with learning and memorizing processes. In particular, said compositions have revealed to be useful in the treatment of the Alzheimer~s pathology, preferably in the forms of slight-medium intensity.

La présente invention concerne des compositions pharmaceutiques à libération contrôlée de thiamine et leur utilisation en médecine visant à pallier des défauts d'absorption de thiamine ou des carences dans l'organisme en thiamine en tant que telle. Ces compositions se sont montrées utiles dans le traitement des pathologies cérébrales liées aux processus défectueux d'apprentissage et de mémorisation, et notamment dans le traitement de la pathologie d'Alzheimer, de préférence dans des formes à intensité faible à moyenne.

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