Phosphonated rifamycins and uses thereof for the prevention...

C - Chemistry – Metallurgy – 07 – F

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Details

C07F 9/6561 (2006.01) A61K 31/5383 (2006.01) A61K 31/675 (2006.01) A61P 19/00 (2006.01) A61P 31/04 (2006.01) C07D 498/18 (2006.01)

Patent

CA 2618741

The present invention relates to phosphonated Rifamycins, and methods of making and using such compounds. These compounds are useful as antibiotics for prophylaxis and/or the treatment of bone and joint infections, especially for the prophylaxis and/or treatment of osteomyelitis.

La présente invention concerne des rifamycines ainsi que leurs procédés de fabrication et leurs méthodes d'utilisation. Ces composés convient comme antibiotiques pour la prophylaxie et/ou le traitement de infections des os et des articulations, en particulier en ce qui concerne l'ostéomyélite.

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