Methods of decreasing vascular calcification using il-1...

Details Methods of decreasing vascular calcification using il-1... Methods of decreasing vascular calcification using il-1...

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2624648

The present invention relates to methods of decreasing, inhibiting, or preventing vascular calcification in subjects by administering IL-1 inhibitors. IL-1 inhibitors useful in this invention include anakinra, IL-1 antibodies, IL-1RI antibodies, IL-1 trap molecules, soluble IL-1 receptors, and anti-IL-1/IL-1R peptides and peptibodies.

La présente invention concerne des méthodes de réduction, d'inhibition ou de prévention de la calcification vasculaire chez des sujets par administration d'inhibiteurs de l'IL-1. Les inhibiteurs de l'IL-1 utilisés dans l'invention comprennent l'anakinra, les anticorps de l'IL-1, les molécules de capture de l'IL-1, les récepteurs solubles de l'IL-1, et les peptides et les corps de peptides anti-IL-1/IL-1R.

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