A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/437 (2006.01) A61K 31/519 (2006.01)
Patent
CA 2425672
The invention relates to the use of the compounds of the general structure (I), or the pharmaceutically acceptable salts thereof, wherein X represents CR4 or N, Y represents CR5 or N, and X and Y are not simultaneously N, and W represents N or NR8. The novel compounds are used for producing a medicament for inhibiting NO synthase, for treating migraine and for treating septicemic shock, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's chorea, inflammations, inflammatory pains, cerebral ischemia, diabetes, meningitis, arteriosclerosis and/or for wound healing.
La présente invention concerne l'utilisation de composés de structure générale (I) ou de leurs sels acceptables d'un point de vue pharmaceutique, structure dans laquelle X représente CR<4> ou N, Y représente CR<5> ou N, X et Y ne représentant pas N en même temps, et W représente N ou NR<8>, dans la production d'un médicament qui sert à inhiber la NO-synthase, à traiter la migraine et à traiter le choc septique, la sclérose en plaque, la maladie de Parkinson, la maladie d'Alzheimer, la maladie de Huntington, les inflammations, les douleurs inflammatoires, l'ischémie cérébrale, le diabète, la méningite, l'artériosclérose et/ou qui sert à la cicatrisation.
Hennies Hagen-Heinrich
Schneider Johannes
Sundermann Bernd
Sundermann Corinna
Fetherstonhaugh & Co.
Grunenthal Gmbh
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