Heterotricyclic derivatives, process for their preparation...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/06 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 513/06 (2006.01)

Patent

CA 2128779

2128779 9315083 PCTABS00024 Heterotricyclic derivatives of formula (I) wherein R1 is hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, nitro, amino or protected amino, R2 is hydroxy, protected hydroxy, halogen, amino or protected amino, R3 is hydrogen or an organic group, R4 is hydrogen or lower alkyl, R8 is hydrogen or lower alkyl, and -Z- is -O- or a group of formula (II) (in which n is 0, 1 or 2), and pharmaceutically acceptable salts thereof which are useful as a medicament.

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